Why the study?
Does isoflurane alter AngII-induced intracellular Ca2+ mobilization in aortic vascular smooth muscle cells from hypertensive and normotensive rats?
Does isoflurane alter AngII-induced intracellular Ca2+ mobilization in aortic vascular smooth muscle cells from hypertensive and normotensive rats?
Isoflurane decreases AngII-induced calcium mobilization in vascular smooth muscle cells via microtubular network interaction, suggesting altered vascular response to AngII during anesthesia.
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Isoflurane may differentially affect AngII vascular signaling by strain; leaves open translation to anesthetic management in hypertensive patients.
Samain et al. (2002) studied this question.
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