Why the study?
Does antihypertensive monotherapy affect quality of life in patients with stable arterial hypertension?
Does antihypertensive monotherapy affect quality of life in patients with stable arterial hypertension?
Answers are grounded in this paper and cite their sources.
Common antihypertensive monotherapies effectively lower blood pressure without negatively impacting patient quality of life.
Aim. To study effect of antihypertensive drugs on quality of life (QoL) of patients with stable arterial hypertension (HT). Material and methods. Results of some studies with similar design involving totally 170 patients with HT, aged 57,2±8,8 y.o., were analyzed. HT duration was 11,2±8,3 years. Patients received antihypertensive monotherapy with diltiazem, amlodipine, enalapril, lisinopril, metoprolol and telmisartan during 1-3 months. 24-hour blood pressure (BP) monitoring, QoL was performed before and after treatment. Results. All antihypertensive drugs significantly reduced systolic and diastolic BP and did not affect QoL. ACE inhibitors similarly improved QoL. Conclusion. Antihypertensive drugs (diltiazem, amlodipine, enalapril, lisinnopril, metoprolol, telmisartan) do not worsen QoL of patients with HT.
No takes yet. Share an insight, caveat, or question.
Андреева et al. (2009) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: