September 1, 2003AnesthesiologyOpen Access

Sustained Ventricular Tachycardia in Long QT Syndrome: Is Propofol the Culprit?

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Population

1 28-year-old man with chronic osteomyelitis of the right femur, with no prior cardiac history or family…

Design

Case_report

Follow-up

24 hours in intensive care unit

Authors

VRVimi RewariAll India Institute of Medical Sciences HKHiralal Kaul

Discussion

Member takes

Implication

Propofol warrants caution in suspected long QT syndrome; this case report leaves open causality and needs confirmation.

Structured PICO

Population

1 28-year-old man (62 kg) with chronic osteomyelitis of the right femur, with no prior cardiac history or family history of sudden death or long QT syndrome, undergoing surgical debridement.

Intervention

Propofol 60 mg bolus (administered for suspected light plane of anesthesia, following initial induction with fentanyl 100 μg and propofol 120 mg)

Outcome

Development of polymorphic ventricular tachycardia and ventricular fibrillationsafety

Propofol administration may trigger life-threatening polymorphic ventricular tachycardia in patients with undiagnosed long QT syndrome.

Limitations

Cause-and-effect relationship between propofol and ventricular tachycardia is not definitively established

Cite This Study

Rewari et al. (2003) studied this question.

synapsesocial.com/papers/6a76fa7e2e130d02afec4ce5 https://doi.org/10.1097/00000542-200309000-00054

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Sustained Ventricular Tachycardia in Long QT Syndrome: Is Propofol the Culprit?

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Sustained Ventricular Tachycardia in Long QT Syndrome: Is Propofol the Culprit?

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider