December 20, 2004IEEE Transactions on Biomedical Engineering

Insulin Kinetics in Type-1 Diabetes: Continuous and Bolus Delivery of Rapid Acting Insulin

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Why the study?

What are the kinetic characteristics of insulin lispro delivered via bolus and continuous subcutaneous insulin infusion in patients with type-1 diabetes?

Structured PICO

What are the kinetic characteristics of insulin lispro delivered via bolus and continuous subcutaneous insulin infusion in patients with type-1 diabetes?

Population

7 subjects with type-1 diabetes treated by continuous subcutaneous insulin infusion (CSII) with insulin lispro

Intervention

Insulin lispro delivered via bolus and continuous subcutaneous insulin infusion (CSII)

Outcome

Insulin kinetics (absorption rate, degradation, distribution) during prandial and postprandial conditions over 12 hourssurrogate

Discussion

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Implication

Insulin lispro absorption during continuous and bolus delivery is best described by a model incorporating both slow and fast absorption channels along with local degradation.

Cite This Study

Wilinska et al. (2004) studied this question.

synapsesocial.com/papers/6a77079bd3a6aa87c6bd86e7 https://doi.org/10.1109/tbme.2004.839639

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Implication

Insulin lispro absorption during continuous and bolus delivery is best described by a model incorporating both slow and fast absorption channels along with local degradation.

Insulin Kinetics in Type-1 Diabetes: Continuous and Bolus Delivery of Rapid Acting Insulin

Structured PICO

Discussion

Implication

Cite This Study

Insulin Kinetics in Type-1 Diabetes: Continuous and Bolus Delivery of Rapid Acting Insulin

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider