What question did this study set out to answer?

To determine the contamination rate of blood cultures and establish laboratory criteria that differentiate true bacteremia from sample contamination.

July 1, 1972Archives of Internal Medicine

Evaluation of Positive Blood Cultures

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Authors

RMRob Roy MacGregorUniversity of Southern California

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Implication

Retrospective review reveals laboratory criteria distinguishing bacteremia from contamination in hospitalized patients, highlighting repeat draws and pour-plate assays.

Key Points

To determine the contamination rate of blood cultures and establish laboratory criteria that differentiate true bacteremia from sample contamination.
Reviewed blood culture records at a general hospital and classified episodes as bacteremia or contamination based strictly on clinical data.
Correlated clinical classifications with laboratory parameters, including multiple positive cultures, pour-plate culture results, and specific microbial identifications.
Multiple positive cultures occurred in 69% of patients with true bacteremia who were tested more than once, compared with 11% of contaminated cases.
Pour-plate cultures were positive in 68% of true bacteremic episodes versus 5.8% of contaminated cultures.
Certain microbial species were exclusively associated with either true bacteremia or contamination.

Cite This Study

Rob Roy MacGregor (1972) studied this question.

synapsesocial.com/papers/6a771227df493903fd1ea4e6 https://doi.org/10.1001/archinte.1972.03650010072013

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Implication

Retrospective review reveals laboratory criteria distinguishing bacteremia from contamination in hospitalized patients, highlighting repeat draws and pour-plate assays.

Evaluation of Positive Blood Cultures

Discussion

Member takes

Implication

Key Points

Cite This Study

Evaluation of Positive Blood Cultures

Discussion

Member takes

Implication

Key Points

Cite This Study

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