What question did this study set out to answer?

To examine the historical, regulatory, and commercial factors that have prevented the availability of low-cost generic insulin nearly a century after its discovery.

March 18, 2015New England Journal of MedicineOpen Access

Why Is There No Generic Insulin? Historical Origins of a Modern Problem

View Full Paper

Ask AI

Bookmark

Authors

JGJeremy A. GreeneJohns Hopkins University KRKevin R. RiggsUniversity of Alabama at Birmingham

Discussion

Member takes

Implication

Policy review uncovers regulatory and patent mechanisms limiting generic insulin in the United States, highlighting enduring market barriers affecting diabetes care.

Key Points

To examine the historical, regulatory, and commercial factors that have prevented the availability of low-cost generic insulin nearly a century after its discovery.
Historical and health policy evaluation of insulin development, patent protections, and drug pricing structures in the United States.
Analysis of regulatory frameworks governing generic biological agents and market entry barriers for non-brand manufacturers.
Identified that iterative technological shifts, patent extensions on delivery devices, and biological manufacturing barriers have continuously delayed generic competition.
Highlighted that despite insulin's 1921 discovery, approximately six million U.S. patients with diabetes remain entirely reliant on costly brand-name formulations.

Cite This Study

Greene et al. (2015) studied this question.

synapsesocial.com/papers/6a771b88576efb0ddaf716e4 https://doi.org/10.1056/nejmms1411398

View Full Paper

Ask AI

Bookmark

Implication

Policy review uncovers regulatory and patent mechanisms limiting generic insulin in the United States, highlighting enduring market barriers affecting diabetes care.

Why Is There No Generic Insulin? Historical Origins of a Modern Problem

Discussion

Member takes

Implication

Key Points

Cite This Study

Why Is There No Generic Insulin? Historical Origins of a Modern Problem

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider