Why the study?
Does left ventricular hypertrabeculation/noncompaction increase the risk of stroke or embolism compared to matched controls?
Does left ventricular hypertrabeculation/noncompaction increase the risk of stroke or embolism compared to matched controls?
Answers are grounded in this paper and cite their sources.
LVHT alone does not appear to be an independent risk factor for stroke or embolism and does not warrant oral anticoagulation unless associated with systolic dysfunction.
Left ventricular hypertrabeculation/noncompaction (LVHT) is reported to be associated with embolism. This retrospective study assessed the number of strokes/embolisms in 62 patients with LVHT and in 62 control patients matched with regard to age, sex and left ventricular systolic function. The incidence of strokes or embolism was 10% in patients with LVHT and 15% in controls. LVHT by itself does not seem to be a risk factor for stroke or embolism and thus is not an indication for oral anticoagulation. However, if LVHT is associated with systolic dysfunction, oral anticoagulation should be considered.
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Stöllberger et al. (2004) studied this question.
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