Why the study?
In the relationship between periodontitis and CHD, the mechanistic role of subclinical atherosclerosis remains incompletely understood.
Does severe periodontitis increase the risk of incident CHD events and subclinical atherosclerosis in a general population cohort?
Population
29 056 SCAPIS participants
Comparison
Severe periodontitis vs no severe periodontitis
Design
Registry-linked cohort study
Key result
Severe periodontitis was associated with a higher risk of incident coronary heart disease events (HR 1.42; 95% CI 1.03-1.97) and severe coronary artery calcium scores (OR 1.69; 95% CI 1.39-2.06).
Authors
Loading...
Severe periodontitis was associated with subclinical coronary atherosclerosis and EAT attenuation; leaves open mediation of incident CHD.
Cohort (n=29,056)
Yes
Does severe periodontitis increase the risk of incident CHD events and subclinical atherosclerosis in a general population cohort?
Hazard Ratio: 1.42 (95% CI 1.03–1.97)
Severe periodontitis is associated with subclinical coronary atherosclerosis, epicardial adipose tissue inflammation, and an increased risk of incident coronary heart disease events.
Teleka et al. (2026) conducted a cohort in Periodontitis and coronary heart disease (n=29,056). Severe periodontitis vs. No severe periodontitis was evaluated on Incident CHD events (HR 1.42, 95% CI 1.03-1.97). Severe periodontitis was associated with a higher risk of incident coronary heart disease events (HR 1.42; 95% CI 1.03-1.97) and severe coronary artery calcium scores (OR 1.69; 95% CI 1.39-2.06).