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April 1, 2004The Journal of ImmunologyOpen Access

The Inositol 3-Phosphatase PTEN Negatively Regulates Fcγ Receptor Signaling, but Supports Toll-Like Receptor 4 Signaling in Murine Peritoneal Macrophages

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Authors

XCXianhua CaoThe Ohio State UniversityWGWei GuoSun Yat-sen UniversityHFHuiqing FangBethune International Peace Hospital

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Cao et al. (2004) studied this question.

synapsesocial.com/papers/6a771edb6789de8d0af70629https://doi.org/10.4049/jimmunol.172.8.4851
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Also Consider

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  1. 1Differentiation Stage-Specific Inhibition of the Raf-MEK-ERK Pathway by Akt1999 · 771 citations
  2. 2Molecular Basis of the Recruitment of the SH2 Domain-containing Inositol 5-Phosphatases SHIP1 and SHIP2 by FcγRIIB2000 · 101 citations
  3. 3Inhibition of Phosphatidylinositol 3-Kinase Induces Nitric-oxide Synthase in Lipopolysaccharide- or Cytokine-stimulated C6 Glial Cells1999 · 118 citations
  4. 4SHIP-2 Inositol Phosphatase Is Inducibly Expressed in Human Monocytes and Serves to Regulate Fcγ Receptor-mediated Signaling2003 · 42 citations