Why the study?
Do genetic polymorphisms in candidate genes affect warfarin dose requirements in the Han-Chinese population?
Do genetic polymorphisms in candidate genes affect warfarin dose requirements in the Han-Chinese population?
Incorporating PROC and EPHX1 polymorphisms into warfarin dosing algorithms could improve dose prediction accuracy in the Han-Chinese population.
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May refine Han-Chinese warfarin dosing models with PROC/EPHX1; hypothesis-generating and needs prospective validation.
Lee et al. (2009) studied this question.
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