Key result
Lower serial systemic vascular resistance index and higher vasoactive-inotropic score were associated with fatality in children with refractory septic shock (both p < 0.05).
Why the study?
Refractory septic shock causes severe morbidity and mortality in children, and hemodynamic-based resuscitation is important to identify poor prognosis early for timely interventions.
What are the hemodynamic predictors of mortality in children with refractory septic shock?
Design
Observational hemodynamic monitoring study
Follow-up
first 72 h after PICU admission
Authors
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May aid risk stratification in pediatric refractory septic shock; hypothesis-generating and requires prospective validation.
Observational (n=33)
What are the hemodynamic predictors of mortality in children with refractory septic shock?
p-value: p=< 0.05
In pediatric refractory septic shock, lower systemic vascular resistance index (SVRI) and higher vasoactive-inotropic score (VIS) are early predictors of mortality.
Lee et al. (2022) conducted an observational in Pediatric refractory septic shock (n=33). Hemodynamic parameters (SVRI and VIS) was evaluated on Fatality from septic shock (p=< 0.05). Lower serial systemic vascular resistance index and higher vasoactive-inotropic score were associated with fatality in children with refractory septic shock (both p < 0.05).
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