A Review of Current Literature of Interest to the Office-Based Anesthesiologist

Mark A. Saxen

doi:10.2344/825121

January 1, 2023Anesthesia ProgressOpen Access

A Review of Current Literature of Interest to the Office-Based Anesthesiologist

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Structured PICO

P

Population

Various populations including children undergoing complex congenital cardiac surgery (n=110), children receiving lidocaine airway topicalization (survey of 1,501 providers), children receiving general anesthesia (meta-analysis of 10 RCTs, n=1,056), and patients undergoing office-based surgery.

I

Intervention

Various anesthetic agents and protocols, including ketamine exposure, lidocaine airway topicalization, and dexmedetomidine administration.

C

Comparator

Placebo or active comparators (specifically in the dexmedetomidine meta-analysis).

O

Outcome

Neurodevelopmental scores at 18 months (Bayley III), local anesthetic systemic toxicity, and perioperative respiratory adverse events (PRAEs).safety

Limitations

Neurodevelopmental deficits in higher cognitive tasks may not be apparent until later in life
Bayley scales would not be able to detect executive function deficits at 18 months of age
In utero brain maturation is delayed in most children with congenital heart disease
Dexmedetomidine meta-analysis has a small sample size, lacks information regarding airway management, and has a significant potential for bias

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Implication

This literature review highlights critical safety considerations in pediatric and office-based anesthesia, noting potential dose-dependent motor deficits with ketamine in congenital heart surgery and the efficacy of dexmedetomidine in preventing respiratory adverse events.

Abstract

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Cite This Study

Mark A. Saxen (2023) studied this question.

synapsesocial.com/papers/6a772596e29fd788c9f71589 https://doi.org/10.2344/825121

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A Review of Current Literature of Interest to the Office-Based Anesthesiologist

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

A Review of Current Literature of Interest to the Office-Based Anesthesiologist

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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