Why the study?
Does sevoflurane anaesthesia increase emergence agitation compared to halothane in paediatric outpatients having no surgical intervention?
Does sevoflurane anaesthesia increase emergence agitation compared to halothane in paediatric outpatients having no surgical intervention?
Sevoflurane anesthesia is associated with a significantly higher incidence of emergence agitation compared to halothane in pediatric patients undergoing non-painful procedures like MRI.
Answers are grounded in this paper and cite their sources.
Supports preferring halothane over sevoflurane in pediatric non-surgical outpatients to reduce emergence delirium; extends RCT evidence on volatile agent recovery profiles.
This study was designed to compare the emergence characteristics of sevoflurane with halothane anaesthesia in paediatric patients having no surgical intervention. We randomized 32 ASA I or II paediatric outpatients scheduled for magnetic resonance imaging scans to receive either halothane or sevoflurane anaesthesia. The primary outcome measure was the percentage of patients with emergence agitation, as defined by two different criteria. Time to discharge from the postanaesthesia care unit (PACU) and the secondary recovery unit (SRU) were compared. Sevoflurane patients had a greater incidence of emergence delirium when a high threshold for agitation was defined (33% vs. 0%, P = 0.010) and a lower threshold for agitation was applied (80% vs. 12%, P<0.0001). Discharge times from the PACU and the SRU were not different. We conclude that there is an increased incidence of emergence agitation with sevoflurane anaesthesia compared to halothane independent of any painful stimulus.
No takes yet. Share an insight, caveat, or question.
Cravero et al. (2000) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: