Key result
Recent mechanistic insights into the structure and function of lipoprotein lipase have highlighted its posttranslational regulators as potential therapeutic targets for lipid-lowering agents.
Why the study?
To discuss recent developments in the structure, function, and physiology of lipoprotein lipase and its regulators being targeted for therapy.
Design
Review
Authors
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Posttranslational LPL regulators remain investigational; leaves open their viability as lipid-lowering targets pending clinical trials.
Recent insights into the structure and function of lipoprotein lipase and its regulators highlight new therapeutic targets for lipid-lowering agents to prevent hypertriglyceridemic pancreatitis and cardiovascular disease.
Basu et al. (2020) conducted a review in Hypertriglyceridemia. Recent mechanistic insights into the structure and function of lipoprotein lipase have highlighted its posttranslational regulators as potential therapeutic targets for lipid-lowering agents.
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