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March 1, 1955Circulation ResearchOpen Access

Venomotor Tone in Hemorrhage and Shock

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Population

Anesthetized dogs (intestinal loops)

Design

Preclinical

Authors

RARobert AlexanderBowling Green State University

Discussion

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Implication

May contribute to decompensation in shock; hypothesis-generating in canines, human relevance untested.

Structured PICO

P
Population
Anesthetized dogs (intestinal loops)
I
Intervention
Hemorrhage and shock induction
O
Outcome
Venomotor tone index (measured by volumes of blood required to produce specified changes in venous pressure)surrogate

In a canine model, hemorrhagic shock leads to a deficiency in venomotor compensation, which may contribute to venous pooling and circulatory failure.

Cite This Study

Robert Alexander (1955) studied this question.

synapsesocial.com/papers/6a7729e24fe2e6ffd8ec7574https://doi.org/10.1161/01.res.3.2.181
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Distensibility Characteristics of the Portal Vascular Bed1953 · 52 citations
  2. 2Relation of Structure to Function of the Tissues of the Wall of Blood Vessels1954 · 801 citations
  3. 3OMENTAL CIRCULATION IN MORPHINIZED DOGS SUBJECTED TO GRADED HEMORRHAGE1944 · 72 citations