Key result
p-POSSUM and Mannheim Peritonitis Index demonstrated fair diagnostic performance in predicting in-hospital mortality with AUCs of 0.756 and 0.757, respectively, outperforming the Jabalpur Peritonitis Index.
Why the study?
Risk scoring systems are needed to enable accurate prognostication, compare surgical outcomes, and help patients make informed health decisions.
Cohort (n=235)
No
Effect estimate: AUC 0.756 (95% CI 0.688-0.823)
p-value: p=<0.001
p-POSSUM and Mannheim Peritonitis Index demonstrate fair diagnostic performance for predicting mortality in secondary peritonitis, whereas the Jabalpur Peritonitis Index is not suitable.
May inform risk stratification in secondary peritonitis; leaves open optimal scoring system pending prospective validation.
BACKGROUND : Risk scoring systems are required to allow accurate prognostication, compare outcomes of surgery and allow patients to make informed decisions about their health. This prospective study compares the p-POSSUM (Portsmouth modification to Physiological and operative severity score for enumeration of mortality ), Mannheim Peritonitis Index and Jabalpur Peritonitis Index for their utility in predicting mortality in patients with peritonitis. METHODS : Perioperative data was collected from 235 patients with secondary peritonitis and used to calculate p-POSSUM, MPI and JPI scores. The accuracy of the 3 scores was compared using receiver operator characteristic curves. RESULTS : p-POSSUM and Mannheim Peritonitis Index were similar in their accuracy with area under the curve (AUC) values of 0.756 and 0.757. Jabalpur Peritonitis Index had an AUC of 0.665. Conclusion: p-POSSUM and Mannheim Peritonitis Index can be used to predict mortality in patients with secondary peritonitis. Jabalpur Peritonitis Index is not suited for this purpose. Further studies are required to improve the diagnostic performance of p-POSSUM and MPI in patients with secondary peritonitis.
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Pathak et al. (2023) conducted a cohort in Secondary peritonitis (n=235). p-POSSUM, Mannheim Peritonitis Index, and Jabalpur Peritonitis Index was evaluated on In-hospital mortality (AUC 0.756, 95% CI 0.688-0.823, p=<0.001). p-POSSUM and Mannheim Peritonitis Index demonstrated fair diagnostic performance in predicting in-hospital mortality with AUCs of 0.756 and 0.757, respectively, outperforming the Jabalpur Peritonitis Index.
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