Key result
In individuals with an ICD after atrial baffle procedure for d-TGA, the rate of appropriate therapies was low (10% in primary prevention) and exceeded by inappropriate discharges (24%).
Why the study?
What are the rates of appropriate therapies, inappropriate discharges, and complications following ICD implantation in patients with d-TGA after atrial baffle procedure?
Cohort (n=33)
Yes
What are the rates of appropriate therapies, inappropriate discharges, and complications following ICD implantation in patients with d-TGA after atrial baffle procedure?
In patients with d-TGA after atrial baffle procedure, ICDs are frequently implanted for primary prevention but are associated with a low rate of appropriate therapies and a high rate of inappropriate shocks and lead complications.
May warrant selective primary-prevention ICD use post-atrial baffle for d-TGA; leaves open refined risk stratification in prospective studies.
BACKGROUND: Sudden cardiac death (SCD) is the most important cause of late mortality after atrial baffle procedure for d-transposition of the great arteries (d-TGA). Experience with internal cardioverter defibrillator (ICD) therapy in this population is limited. We conducted a multicenter cohort study to determine the current state of ICD therapy in individuals after atrial baffle procedure. METHODS: Demographic and clinical data as well as data on device implantation, programming, ICD discharges, and complications after atrial baffle procedure for d-TGA from four German centers were analyzed retrospectively. RESULTS: ICD implantation was undertaken in 33 subjects. ICD implantation was undertaken as primary prevention in 29 (88%) and secondary prevention in four (12%) individuals. There were 21 (64%) subjects with atrial reentrant tachycardia (IART). During a median follow-up of 4.8 years, seven appropriate ICD therapies were delivered in three (10%) individuals with primary prevention indication. No appropriate shocks were documented in subjects with secondary prevention indication. A total of 12 inappropriate ICD discharges occurred in eight (24%) individuals due to IART (n = 6) or lead failure (n = 2). ICD-related complications were noted in seven individuals (21%): lead dislodgement/failure in five (15%) and ICD infection in two subjects (6%). CONCLUSIONS: The majority of individuals received an ICD for primary prevention of SCD, thus representing a liberal attitude of physicians for ICD implantation. During a median follow-up of 4.8 years, the rate of appropriate ICD therapies was low and clearly exceeded by inappropriate ICD discharges. Lead failure and IART were present in >20% of the individuals and were frequent reasons for inappropriate ICD discharges. Facing these results, rigorous treatment of IART and careful ICD programming seems mandatory.
No takes yet. Share an insight, caveat, or question.
Backhoff et al. (2016) conducted a cohort in d-transposition of the great arteries (d-TGA) after atrial baffle procedure (n=33). Internal cardioverter defibrillator (ICD) therapy was evaluated on Appropriate ICD therapies in primary prevention. In individuals with an ICD after atrial baffle procedure for d-TGA, the rate of appropriate therapies was low (10% in primary prevention) and exceeded by inappropriate discharges (24%).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: