Key result
Non-transplant surgical management strategies, including coronary revascularization and ventricular reconstruction, should be considered for end-stage heart failure before transplantation.
Non-transplant surgical interventions offer alternative management strategies for end-stage heart failure patients prior to considering cardiac transplantation.
May support pre-transplant surgical strategies in end-stage HF; leaves open need for prospective trials before practice change.
Despite a variety of available medical therapies and electrophysiological interventions, many heart failure patients still have a poor quality of life and a poor prognosis. Cardiac transplantation is currently the main treatment for end-stage heart failure in Taiwan but it is sometimes accompanied by rejection, immune compromise, and the adverse side effects of antirejection drugs. In addition, there is a shortage of donor grafts worldwide. For these reasons, other surgical interventions that alleviate ischemia and valvular dysfunction, and also reverse ventricular remodeling, should be considered before transplantation is advised. In this review, we discuss current nontransplant surgical management strategies for end-stage heart failure in terms of coronary revascularization, mitral reconstruction, ventricular reconstruction, and stem-cell regeneration of the myocardium.
No takes yet. Share an insight, caveat, or question.
Tsai et al. (2012) conducted a review in End-stage heart failure. Non-transplant surgical management strategies was evaluated. Non-transplant surgical management strategies, including coronary revascularization and ventricular reconstruction, should be considered for end-stage heart failure before transplantation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: