Virus Myopericarditis

Editorial Notes1 November 1968Virus MyopericarditisA. MARTIN LERNER, M.D., F.A.C.P.A. MARTIN LERNER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-69-5-1068 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptOutbreaks of coxsackievirus infections such as that described recently by Helin, Savola, and Lapinleimu (1) at the Kuopio Central Hospital in Finland indicate that involvement of the heart may be frequent. Their paper, published in theBritish Medical Journal, reports on patients with coxsackievirus group B, type 5 infections who required hospitalization during the latter half of 1965. There were 18 with carditis, 20 with aseptic meningitis, 10 with pleurodynia, and 6 with encephalitis. Those with evidence of myocardial, or pericardial disease, or both (myopericarditis), were mostly young adults (mean age, 28 years) with men being twice as commonly afflicted...References1. HELINSAVOLALAPINLEIMU MJK: Cardiac manifestations during a coxsackie B5 epidemic. Brit. Med. J. 3: 97, 1968. CrossrefMedlineGoogle Scholar2. HORSTMANN DM: Clinical virology. Amer. J. Med. 38: 738, 1965. CrossrefMedlineGoogle Scholar3. LERNERLEVINFINLAND AMHSM: Age and susceptibility of mice to Coxsackie A viruses. J. Exp. Med. 115: 745, 1962. CrossrefMedlineGoogle Scholar4. GRODUMSDEMPSTER EIG: The age factor in experimental coxsackie B-3 infection. Canad. J. Microbiol. 5: 595, 1959. CrossrefMedlineGoogle Scholar5. BURCHDEPASQUALESUNMOGABGABHALE GENPSCWJAR: Endocarditis in mice infected with cosackievirus B4. Science 151: 447, 1968. CrossrefGoogle Scholar6. FEDERICILERNERABELMANN EEAMWH: Observations on the course of Coxsackie A-9 myocarditis in C3H mice. Proc. Soc. Exp. Biol. Med. 112: 672, 1963. CrossrefMedlineGoogle Scholar7. WILSONMIRANDACHASONLERNER FMQRJLAM: Residual pathologic changes in the hearts of mice after coxsackie A and B myocarditis (abstract). Bact. Proc. 166, 1968. Google Scholar8. TILLESELSONSHAKAABELMANNLERNERFINLAND JGSHJAWHAMM: Effects of exercise on Coxsackie A9 myocarditis in adult mice. Proc. Soc. Exp. Biol. Med. 117: 777, 1964. CrossrefMedlineGoogle Scholar9. KILBOURNESMARTPOKORNY EDKMBA: Inhibition by cortisone of the synthesis and action of interferon. Nature (London) 190: 650, 1961. CrossrefMedlineGoogle Scholar10. KILBOURNEWILSONPERRIER EDCBD: The induction of gross myocardial lesions by a coxsackie (pleurodynia) virus and cortisone. J. Clin. Invest. 35: 362, 1956. CrossrefMedlineGoogle Scholar11. LERNER AM: An experimental approach to virus myocarditis. Proc. Med. Virol. 7: 97, 1965. MedlineGoogle Scholar12. KIBRICK S: Viral infections of the fetus and newborn. Persp. Virol. Symp. (New York) 2: 140, 1961. Google Scholar13. RABINHASSANJENSENMELNICK ERSAABJL: Coxsackievirus B-3 myocarditis in mice. An electron microscopic, immunofluorescent and virus-assay study. Amer. J. Path. 44: 775, 1964. MedlineGoogle Scholar14. BROWNEVANS GCTN: Serologic evidence of Coxsackievirus etiology of congenital heart disease. JAMA 199: 183, 1967. CrossrefMedlineGoogle Scholar15. BURCHSUNCOLCOLOUGHSOHALDEPASQUALE GESCHLRSNP: Coxsackie B viral myocarditis and valvulitis identified in routine autopsy specimens by immunofluorescent techniques. Amer. Heart J. 74: 13, 1967. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Dr. Lerner was supported in this study by grants AI 05721 and Al 00261, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.; grant 67-677, the American Heart Association, New York, N. Y.; and a grant from the Michigan Heart Association, Detroit, Mich. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCoxsackie virus myopericarditisThe role of Coxsackie Group B virus infections in sporadic myopericarditisDifferential diagnosis of cardiomyopathiesKlinik der MyokarditisAktuelle Probleme der Pathogenese und Therapie verschiedener Schockformen in der inneren Medizin (Symposion) 1 November 1968Volume 69, Issue 5Page: 1068-1070KeywordsEncephalitisHeartHeart diseasesHospitalizationsInfectious diseasesLongitudinal studiesMeningitisMyocarditisPericardial diseasesYoung adults Issue Published: 1 November 1968 PDF DownloadLoading ...