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Editorial
This 1959 editorial reviews the characteristics, transmission, and clinical manifestations of Coxsackie viruses in humans, including their role in myocarditis.
Editorial1 April 1959COXSACKIE VIRUSES AS A CAUSE OF DISEASE IN MANPAUL W. CLOUGH, M.D.PAUL W. CLOUGH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-50-4-1062 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince a Coxsackie virus was first recovered and described by Dalldorf in 1948 much information has been obtained both regarding the characteristics of the virus, its occurrence under natural conditions and the manifestations of infection in man. Some of the earlier studies were reviewed here in 1951.1The Coxsackie viruses, like the polioviruses and ECHO viruses, are enteric viruses. They are acquired presumably by ingestion, they are disseminated in the feces, and they have been found in sewage and in pools of flies, doubtless as a result of fecal contamination. They are worldwide in distribution. They have been recovered during...1 Editorial: Coxsackie viruses, Ann. Int. Med. 34: 257-263, 1951. LinkGoogle Scholar2 Dalldorf G: The Coxsackie viruses, Bull. New York Acad. Med. 26: 329-335, 1950. MedlineGoogle Scholar3 PappenheimerKunzRichardson AMLJS: Passage of Coxsackie virus (Connecticut-5 strain) in adult mice with production of pancreatic disease, J. Exper. Med. 94: 45-64, 1951. CrossrefMedlineGoogle Scholar4 DalldorfGifford GR: Adaptation of Group B Coxsackie viruses to adult mouse pancreas, J. Exper. Med. 96: 491-497, 1952. CrossrefMedlineGoogle Scholar5 HuebnerRisserBellBeemanBeigelmanStrong RJJAJAEAPMJC: Epidemic pleurodynia in Texas: a study of 22 cases, New England J. Med. 248: 267-274, 1953. CrossrefMedlineGoogle Scholar6 GordonLennetteSandrock RBEHRS: The varied clinical manifestations of Coxsackie virus infections, Arch. Int. Med. 103: 63-75, 1959. CrossrefGoogle Scholar7 Sneierson H: Pleurodynia (Coxsackie virus infection Group B) and acute abdominal conditions in children, Am. J. Surg. 88: 393-398, 1954. CrossrefMedlineGoogle Scholar8 SyvertonMcLeanMartins da SilvaDoanyCooneyKleinmanBauer JTDMMHBMHH: Attack of aseptic meningitis caused by Coxsackie B 5 virus, J. A. M. A. 164: 2015-2019 (Aug. 31) 1957. CrossrefMedlineGoogle Scholar9 HummelerKirkOstapiak KDM: Aseptic meningitis caused by Coxsackie virus with isolation of virus from the cerebrospinal fluid, J. A. M. A. 156: 676-679, 1954. CrossrefMedlineGoogle Scholar10 BayerGear PJ: Virus meningo-encephalitis in South Africa; study of cases admitted to Johannesburg Fever Hospital, South African J. Lab. and Clin. Med. 1: 22-35, 1955 MedlineGoogle Scholar11 Stoeber E: Weitere Untersuchungen über epidemische Myocarditis (Schwielenherz) des Säuglings, Ztschr. f. Kinderh. 71: 319-356, 592-623, 1952. CrossrefGoogle Scholar12 MontgomeryGearPrinslooKahnKirsch JJFRMZG: Myocarditis of the newborn: an outbreak in a Maternity Home in Southern Rhodesia associated with Coxsackie Group B virus infection, South African M. J.: 29: 608, 1955. MedlineGoogle Scholar13 JavettHeymannMundelPeplerLurieGearMeasrochKirsch SNSBWJHIJVZ: Myocarditis in the newborn infant. A study of an outbreak associated with a Coxsackie Group B virus infection in a maternity home in Johannesburg, J. Pediat. 48: 1-22, 1956. CrossrefMedlineGoogle Scholar14 Van Creveldde Jager SH: Myocarditis in newborns caused by Coxsackie virus. Clinical and pathological data, Ann. paediat. 187: 100-112, 1956. MedlineGoogle Scholar15 KibrickBenirschke SK: Acute aseptic myocarditis and meningoencephalitis in newborn child infected with Coxsackie virus Group B, Type 3, New England J. Med. 255: 883-889, 1956. CrossrefMedlineGoogle Scholar16 KaganBernkopf HH: Pericarditis caused by Coxsackie virus B, Ann. paediat. 189: 44-50, 1957. MedlineGoogle Scholar17 KilbourneWilsonPerrier EDCBD: The induction of gross myocardial lesions by a Coxsackie (pleurodynia) virus and cortisone, J. Clin. Investigation 35: 362-370, 1956. CrossrefMedlineGoogle Scholar18 MelnickKaplanZabinContrerasLarkum JLASEGNW: An epidemic of paralytic poliomyelitis characterized by dual infections with poliomyelitis and Coxsackie viruses, J. Exper. Med. 94: 471-492, 1951. CrossrefMedlineGoogle Scholar19 Dalldorf G: The sparing effect of Coxsackie virus infection on experimental poliomyelitis, J. Exper. Med. 94: 65-71, 1951. CrossrefMedlineGoogle Scholar20 Dalldorf G: Neuropathogenicity of Group A Coxsackie viruses, J. Exper. Med. 106: 69-76, 1957. CrossrefMedlineGoogle Scholar21 DalldorfWeigand GH: Poliomyelitis as a complex infection, J. Exper. Med. 108: 605-616, 1958. CrossrefMedlineGoogle Scholar22 Melnick JL: Enteroviruses, Scientific American 200: 89-97 (Feb.) 1959. (An excellent semipopular but authoritative review.) CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: PAUL W. CLOUGH, M.D. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byViral myocarditisLes infections � virus CoxsackieEncephalitis and Poliomyelitis in the Adult Due to Coxsackie Virus Group B, Type 5 1 April 1959Volume 50, Issue 4Page: 1062-1068KeywordsInfectious diseasesIngestion ePublished: 1 December 2008 Issue Published: 1 April 1959 PDF downloadLoading ...
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