Key result
Alum-adjuvant inactivated EV71 vaccines demonstrated high efficacy, good immunogenicity persistence, and acceptable safety profiles in clinical trials for hand, foot, and mouth disease.
Why the study?
Do alum-adjuvant inactivated EV71 vaccines provide efficacy and safety against hand, foot, and mouth disease?
Population
Populations at risk for hand, foot, and mouth disease (HFMD) caused by Enterovirus A71 (EV71)
Design
Review
Authors
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Supports HFMD prevention strategies in endemic areas; extends trial data but leaves real-world effectiveness open.
Do alum-adjuvant inactivated EV71 vaccines provide efficacy and safety against hand, foot, and mouth disease?
Alum-adjuvant inactivated EV71 vaccines demonstrate high efficacy and acceptable safety, representing a major milestone in controlling hand, foot, and mouth disease.
Zhou et al. (2016) conducted a review in Hand, foot, and mouth disease (HFMD). Alum-adjuvant inactivated EV71 vaccines was evaluated. Alum-adjuvant inactivated EV71 vaccines demonstrated high efficacy, good immunogenicity persistence, and acceptable safety profiles in clinical trials for hand, foot, and mouth disease.