Key result
The combined use of a high-density mapping catheter and a remote magnetic navigation ablation catheter achieved complete pulmonary vein isolation in 100% of patients with no procedural complications.
Why the study?
Is the combined use of a high-density multi-electrode mapping catheter and a magnetically navigated ablation catheter feasible for achieving pulmonary vein isolation in patients with paroxysmal atrial fibrillation?
Observational (n=21)
No
Is the combined use of a high-density multi-electrode mapping catheter and a magnetically navigated ablation catheter feasible for achieving pulmonary vein isolation in patients with paroxysmal atrial fibrillation?
The combined use of a high-density multi-electrode mapping catheter and a magnetically navigated ablation catheter is a feasible and safe strategy for achieving pulmonary vein isolation in patients with paroxysmal atrial fibrillation.
Supports feasibility of combined high-density mapping and remote magnetic navigation for PVI; leaves open comparative efficacy versus standard ablation in randomized trials.
PentaRay s catheters (Biosense Webster, Diamond Bar, CA) create high-density electroanatomical maps, and remote magnetic navigation (RMN) (Niobe Epocht, Stereotaxis Inc., St. Louis, MO) enables intricate manipulation of magnetic ablation catheters. The purpose of this study was to assess the feasibility of PentaRay s used in combination with RMN ablation for pulmonary vein isolation (PVI). In 21 paroxysmal atrial fibrillation (AF) patients undergoing PVI, a PentaRay s catheter was used to map the left atrium in sinus rhythm at baseline and post PVI. The Navigant Ablation History module (Stereotaxis Inc., St. Louis, MO) was used to help create connected ablation lines, pacing from the ablation catheter (ThermoCool RMT, Biosense Webster, Diamond Bar, CA) was performed to examine the presence of exit block, and voltage maps from the PentaRay s were used to demarcate low-voltage areas where bipolar voltages were within 0.25-0.5 mV. This information was assessed to identify potential PVI gaps, and additional ablation points were delivered as necessary. Complete PVI was achieved in 21 out of 21 patients (100%). The average initial mapping time was 12.4 2.7 min spanning 1,726 476 points. Similarly, the average remap time was 14 4.3 min spanning 1,928 842 points. There were no procedural complications associated with this study. This study demonstrates the feasibility of this clinical workflow using both a high-density multi-electrode mapping catheter and an RMN ablation catheter for PVI. The combination might be a useful strategic choice for treatment of AF.
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Hügl et al. (2016) conducted an observational in Paroxysmal atrial fibrillation (n=21). PentaRay high-density mapping catheter combined with remote magnetic navigation ablation was evaluated on Complete pulmonary vein isolation (PVI). The combined use of a high-density mapping catheter and a remote magnetic navigation ablation catheter achieved complete pulmonary vein isolation in 100% of patients with no procedural complications.
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