Key result
IV immunoglobulin infusions are linked to stroke, with ~88% occurring within 24 hours of administration.
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This report characterizes the clinical features of 16 cases of stroke associated with IV immunoglobulin infusions. Fourteen of the strokes occurred within 24 hours of an infusion and 50% of the patients were receiving IV immunoglobulin for the first time. Nine patients had multifocal infarctions. All but one of the patients had stroke risk factors.
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Caress et al. (2003) studied this question. IV immunoglobulin infusions were associated with 16 stroke cases, with 88% (14/16) occurring within 24 hours of administration and 94% (15/16) in patients with pre-existing stroke risk factors.
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