An angiotensin converting enzyme (ACE) inhibitory peptide was isolated, purified from the hydrolysates of duck meat protein. Duck meat protein was hydrolyzed using trypsin at 37℃ for 2 hrs. An ACE inhibitory peptide was purified using membrane filtration, anion exchange chromatography, gel permeation chromatography, fast protein liquid chromatography, normal phase HPLC. The purified inhibitory peptide was identified to be a tetrapeptide, Glu-Asp-Leu-Glu having IC_(50) value of 85.9 μM.
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Kim et al. (2003) studied this question.
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