September 1, 2000Expert Opinion on Pharmacotherapy
Low molecular weight heparins
Comparison
Low molecular weight heparins (LMWHs) vs Unfractionated heparin
Design
Review
Authors
Discussion
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Member takes
Implication
May support expanded LMWH use in VTE and ACS; leaves open prospective validation in current practice.
Structured PICO
I
Intervention
Low molecular weight heparins (LMWHs)
C
Comparator
Unfractionated heparin
LMWHs offer pharmacologic advantages over unfractionated heparin, including more predictable anticoagulant effects and no need for laboratory monitoring, with expanding indications in venous thromboembolism and acute coronary interventions.
Cite This Study
Mejía et al. (2000) studied this question.