Key result
Bridging anticoagulation is not indicated for over 90% of patients receiving warfarin or direct-acting oral anticoagulants during periprocedural interruptions, requiring an immediate change in practice.
Why the study?
Should patients receiving oral anticoagulants receive bridging anticoagulation during periprocedural interruptions?
Should patients receiving oral anticoagulants receive bridging anticoagulation during periprocedural interruptions?
Answers are grounded in this paper and cite their sources.
Bridging anticoagulation during periprocedural interruptions should be avoided in the vast majority of patients on oral anticoagulants due to safety concerns.
Because of the recent publication of several important studies, there has been a major change in how we think about perioperative management of anticoagulation. Because of these changes, existing consensus guidelines are suddenly out of date and can no longer be used as is, particularly the 2012 American College of Chest Physicians Antithrombotic Guidelines, version 9. We estimate that well over 90% of patients receiving warfarin therapy should not receive bridging anticoagulation during periprocedural interruptions of therapy, except under unusual circumstances and with appropriate justification. Accumulating evidence also suggests that bridging is not indicated among patients receiving direct-acting oral anticoagulant therapy. The large number of patients potentially affected represents an important safety concern and requires an immediate change in practice.
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Rose et al. (2015) conducted an editorial in Patients receiving warfarin or direct-acting oral anticoagulant therapy requiring periprocedural interruption. Bridging anticoagulation was evaluated. Bridging anticoagulation is not indicated for over 90% of patients receiving warfarin or direct-acting oral anticoagulants during periprocedural interruptions, requiring an immediate change in practice.
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