Key result
Higher fragment 1 + 2 plasma levels 4 weeks after oral anticoagulant withdrawal were significantly associated with VTE recurrence (P<0.005).
Why the study?
Are fragment 1 + 2 plasma levels after oral anticoagulant therapy discontinuation prognostic for VTE recurrence in patients with VTE?
Cohort (n=139)
Are fragment 1 + 2 plasma levels after oral anticoagulant therapy discontinuation prognostic for VTE recurrence in patients with VTE?
p-value: p=<0.005
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Elevated fragment 1 + 2 plasma levels 4 weeks after oral anticoagulant withdrawal indicate clotting activation and may serve as an independent risk factor for VTE recurrence.
Poli et al. (2004) conducted a cohort in Venous thromboembolism (VTE) (n=139). Higher fragment 1 + 2 (F1 + 2) plasma levels vs. Normal levels of F1 + 2 was evaluated on VTE recurrence (p=<0.005). Higher fragment 1 + 2 plasma levels 4 weeks after oral anticoagulant withdrawal were significantly associated with VTE recurrence (P<0.005).
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