Why the study?
Does monitoring of prothrombin fragment F1+2 predict recurrent venous thromboembolism in patients with a history of venous thrombosis?
Population
253 patients with a history of venous thrombosis followed after discontinuation of oral anticoagulants, and…
Comparison
Monitoring of prothrombin fragment F1+2 levels vs Patients without recurrent thrombosis; healthy…
Design
Cohort
Follow-up
1 year
Authors
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F1+2 monitoring does not predict recurrent VTE after OAC stop; does not support its use and leaves open alternative biomarker studies.
Does monitoring of prothrombin fragment F1+2 predict recurrent venous thromboembolism in patients with a history of venous thrombosis?
Monitoring of prothrombin fragment F1+2 is not suitable for identifying individuals at risk of recurrent venous thrombosis after discontinuation of oral anticoagulants.
Kyrle et al. (1997) studied this question.
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