HEMOGLOBIN D was the fifth human hemoglobin to be described after hemoglobin A (normal adult), hemoglobin F (normal fetal), hemoglobin S (sickle) and hemoglobin C. It was found with hemoglobin S in 2 white siblings with hemoglobin S-D disease.1 , 2 Three additional cases of this disorder have been reported, 2 in Caucasians3 , 4 and 1 in a mulatto.5 A survey of a nearby city found the incidence of hemoglobin D trait to be 0.85 per 1000 Negroes.6 It was suggested that hemoglobin S-D disease was being overlooked in the Negro.Hemoglobin D has the same mobility on filter-paper electrophoresis at pH 8.6 . . .
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McCurdy et al. (1960) studied this question.
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