Key result
The CTA Vasospasm Score on day 5 reliably predicted cerebral infarction due to delayed cerebral ischaemia (AUC 0.89; 95% CI 0.79-0.99) and unfavorable functional outcome.
Why the study?
Delayed cerebral ischaemia is a severe complication of aneurysmal subarachnoid hemorrhage, prompting exploration of whether a computed tomography angiography Vasospasm Score predicts delayed cerebral ischaemia and subsequent poor outcome.
Does the CTA Vasospasm Score predict delayed cerebral ischaemia and functional outcome in patients with aneurysmal subarachnoid hemorrhage?
Population
59 patients with aneurysmal subarachnoid hemorrhage
Comparison
Predictive value of CTA Vasospasm Score across 17 intradural arterial segments
Design
Observational cohort study
Follow-up
6 months
Authors
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May support risk stratification for DCI monitoring in aSAH; leaves open prospective validation before practice change.
Observational (n=59)
Does the CTA Vasospasm Score predict delayed cerebral ischaemia and functional outcome in patients with aneurysmal subarachnoid hemorrhage?
Effect estimate: AUC 0.89 (95% CI 0.79-0.99)
The CTA Vasospasm Score assessed on day 5 is a reliable predictor of delayed cerebral ischemia and poor functional outcome in patients with aneurysmal subarachnoid hemorrhage.
Harst et al. (2021) conducted an observational in aneurysmal subarachnoid hemorrhage (n=59). CTA Vasospasm Score was evaluated on cerebral infarction due to DCI (CI-DCI), radiological and clinical DCI, and unfavorable functional outcome (mRS >2 at 6 months) (AUC 0.89, 95% CI 0.79-0.99). The CTA Vasospasm Score on day 5 reliably predicted cerebral infarction due to delayed cerebral ischaemia (AUC 0.89; 95% CI 0.79-0.99) and unfavorable functional outcome.
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