Why the study?
Does BMI category affect long-term mortality in patients with ischemic stroke?
Population
1,592 consecutive patients with ischemic stroke
Comparison
Body Mass Index categories based on… vs Normal weight
Design
Cohort
Follow-up
median 4 years
Key result
Underweight was independently associated with increased long-term mortality after ischemic stroke (HR 2.79; 95% CI 1.92-4.05), whereas overweight and obesity were not.
Authors
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Supports closer post-stroke monitoring for underweight patients; leaves open whether obesity paradox reflects confounding by initial stroke severity.
Cohort (n=1,592)
Does BMI category affect long-term mortality in patients with ischemic stroke?
Hazard Ratio: 2.79 (95% CI 1.92–4.05)
The obesity paradox in ischemic stroke may be confounded by initial neurological severity, with only underweight independently predicting long-term mortality.
Ryu et al. (2011) conducted a cohort in ischemic stroke (n=1,592). Underweight vs. Normal weight was evaluated on long-term mortality (HR 2.79, 95% CI 1.92-4.05). Underweight was independently associated with increased long-term mortality after ischemic stroke (HR 2.79; 95% CI 1.92-4.05), whereas overweight and obesity were not.