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May 3, 2024International Journal of Stroke

Compared with normal weight, being underweight was associated with increased mortality (RR 1.78, 95% CI 1.60-1.96), whereas being overweight (RR 0.81, 95% CI 0.74-0.89) and obese (RR 0.76, 95% CI 0.72-0.81) were associated with reduced mortality.

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Why the study?

Many studies have explored the impact of body mass index on stroke prognosis, but findings remain inconsistent.

Does body mass index category affect mortality, functional outcomes, and recurrence in patients with stroke?

Population

330,353 stroke patients across 32 cohort studies

Comparison

Underweight, overweight, and obesity vs normal weight

Design

Systematic review and meta-analysis of cohort studies

Authors

JQJiangxia QinTZTong ZhangYCYajing Chen

Discussion

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Overview

Underweight stroke patients show higher mortality and recurrence risk while overweight/obese fare better; leaves open whether BMI modification alters post-stroke outcomes.

Structured PICO

Does body mass index category affect mortality, functional outcomes, and recurrence in patients with stroke?

P
Population
330,353 patients with stroke from 32 cohort studies
I
Intervention
Underweight, overweight, and obesity (BMI categories)
C
Comparator
Normal weight
O
Outcome
Mortality, stroke recurrence, and poor functional outcomes (modified Rankin scale ⩾ 3)hard clinical

In stroke patients, being overweight or obese is associated with decreased mortality and better functional outcomes compared to normal weight, supporting the obesity paradox.

Cite This Study

Qin et al. (2024) studied this question.

synapsesocial.com/papers/6a7c27085d0a07afc93bd894https://doi.org/10.1177/17474930241255031
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