Key result
Catheter-based renal sympathetic denervation reduced office systolic blood pressure by 13.1 mm Hg at 6 months (P<0.01) in patients with mild resistant hypertension.
Why the study?
Does catheter-based renal sympathetic denervation reduce blood pressure in patients with mild therapy-resistant hypertension?
Population
20 consecutive patients with mild therapy-resistant hypertension, mean age 60.6 ± 10.8 years, 45% female.
Design
Cohort
Follow-up
6 months
Authors
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May lower BP in mild resistant hypertension; hypothesis-generating and should not change practice without RCTs.
Cohort (n=20)
Does catheter-based renal sympathetic denervation reduce blood pressure in patients with mild therapy-resistant hypertension?
p-value: p=<0.01
Catheter-based renal sympathetic denervation safely and effectively reduces blood pressure in patients with mild drug-resistant hypertension.
Kaltenbach et al. (2012) conducted a cohort in mild resistant hypertension (n=20). Catheter-based renal sympathetic denervation was evaluated on change in office systolic blood pressure at 6 months (p=<0.01). Catheter-based renal sympathetic denervation reduced office systolic blood pressure by 13.1 mm Hg at 6 months (P<0.01) in patients with mild resistant hypertension.
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