Key result
Time-resolved 4D-CTA visualizes bronchial-to-pulmonary artery collateral supply in CTEPH, confirmed by angiography.
Why the study?
Can time-resolved 4D CT angiography successfully depict systemic collateral supply to the pulmonary artery in a patient with CTEPH?
Case Report (n=1)
No
Can time-resolved 4D CT angiography successfully depict systemic collateral supply to the pulmonary artery in a patient with CTEPH?
4D-CTA can noninvasively evaluate the anatomy and hemodynamics of systemic collaterals in CTEPH, potentially aiding in challenging balloon pulmonary angioplasty interventions.
Supports feasibility of noninvasive collateral assessment in CTEPH; leaves open validation for guiding interventions.
A 49-year-old man with CTEPH (pre-procedural mean pulmonary artery pressure: 36 mmHg) underwent balloon pulmonary angioplasty. Chronic total occlusion of the left inferior pulmonary artery trunk was observed. To evaluate the collateral vessels of the chronic total occlusion, 4D-CTA was performed. The examination was performed using a 256-row detector CT system using the test bolus tracking method. 4D-CTA showed the bronchial artery-to-left inferior pulmonary artery collateral supply, which was confirmed by a selective bronchial artery angiography. The patient's symptoms improved with balloon pulmonary angioplasty of the other stenotic lesions. 4D-CTA can noninvasively evaluate the anatomy and hemodynamics of multiple systemic collaterals simultaneously. This technique can support interventions in systemic artery-to-pulmonary artery collaterals, such as embolization, and could be helpful in challenging balloon pulmonary angioplasty interventions for chronic total occlusion to identify vessel structures distal to the chronic total occlusion and collateral channels for a retrograde approach.
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Tamura et al. (2019) conducted a case report in Chronic thromboembolic pulmonary hypertension (CTEPH) with chronic total occlusion of the left inferior pulmonary artery trunk (n=1). Time-resolved 4D CT angiography (4D-CTA) vs. Selective bronchial artery angiography was evaluated on Depiction of bronchial artery-to-left inferior pulmonary artery collateral supply. Time-resolved 4D-CTA successfully depicted the bronchial artery-to-left inferior pulmonary artery collateral supply in a patient with CTEPH, confirmed by selective angiography (dose 6.46 mSv).
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