Why the study?
CAD tends to present at a younger age with more extensive angiographic involvement, driven by genetic, conventional, metabolic, and non-traditional risk factors.
Systematic Review
Answers are grounded in this paper and cite their sources.
Young South Asian patients with early-onset coronary artery disease frequently present with single-vessel disease and have high rates of modifiable risk factors such as dyslipidemia, high BMI, and smoking.
Coronary artery disease is one of the leading causes of mortality and morbidity in both developed and developing countries. Coronary artery disease (CAD) tends to present at a younger age and has more extensive angiographic involvement, resulting in genetic, conventional, metabolic and non-traditional risk factors. This systematic review provides a qualitative overview of the risk factors, angiographic features, treatments, and complications of Bangladeshi youth with coronary artery disease (CHD). Search PubMed, Embase, and Google Scholar for studies published between the year 2004 to 2022. Identified the paper. Studies conducted in Bangladesh and other countries in patients aged 25 to 65 years were published in English and included information on patients' clinical profiles and risk factors for early-onset CAD. Smoking, dyslipidemia, high BMI, high-sensitivity C-reactive protein, and hyperhomocysteinemia are frequently observed in young CAD patients. Among young patients with coronary artery disease, single-vessel disease was more common than multivessel disease. Complications of coronary artery disease, such as arrhythmias, cardiogenic shock, and heart failure, are also more common in young patients. Coronary angiography findings revealed that more than one-third of the patients had normal coronary arteries, but in the majority of patients they were found to have SVD, DVD, and TVD. In some cases, "TVD & LM" and mild CAD were also detected by her CAG.
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Kawsar et al. (2024) conducted a systematic review in Coronary Artery Disease. Early-onset coronary artery disease risk factors was evaluated on Prevalence of risk factors and angiographic findings.
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