Key result
Tricuspid annular plane systolic excursion correlated with maximal oxygen consumption (R=0.64; P=0.033) and oxygen consumption at the anaerobic threshold (R=0.73; P=0.017) in children with HLHS.
Why the study?
Does TAPSE correlate with exercise capacity in children with hypoplastic left heart syndrome after Fontan operation?
Cohort (n=11)
Does TAPSE correlate with exercise capacity in children with hypoplastic left heart syndrome after Fontan operation?
Effect estimate: R=0.64 for maximal oxygen consumption; R=0.73 for anaerobic threshold
p-value: p=0.033 and 0.017
In children with HLHS after Fontan operation, TAPSE is reproducible, significantly lower than normal, and correlates well with exercise performance.
No takes yet. Share an insight, caveat, or question.
Supports TAPSE as a noninvasive marker of exercise capacity in pediatric HLHS; extends correlations to single-ventricle physiology.
Goldberg et al. (2016) conducted a cohort in Hypoplastic left heart syndrome (HLHS) after Fontan operation (n=11). Tricuspid annular plane systolic excursion (TAPSE) vs. Reference values was evaluated on Correlation of TAPSE with maximal oxygen consumption and oxygen consumption at the anaerobic threshold (R=0.64 for maximal oxygen consumption; R=0.73 for anaerobic threshold, p=0.033 and 0.017). Tricuspid annular plane systolic excursion correlated with maximal oxygen consumption (R=0.64; P=0.033) and oxygen consumption at the anaerobic threshold (R=0.73; P=0.017) in children with HLHS.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: