Key result
Human coronary collateral circulation is prognostically relevant, and understanding its determinants could guide future therapies to promote collateral growth and reduce coronary artery disease.
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Design
Review
Highlights potential for collateral-targeted therapies in CAD; leaves open efficacy pending prospective trials.
The human coronary collateral circulation is prognostically relevant. The understanding of collateral formation and its determinants may guide future therapeutic strategies aiming at promoting collateral growth and functionality, and hence reducing the global burden of coronary artery disease (CAD).
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Stefano F. de Marchi (2014) studied this question. Human coronary collateral circulation is prognostically relevant, and understanding its determinants could guide future therapies to promote collateral growth and reduce coronary artery disease.
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