What question did this study set out to answer?

To evaluate the efficacy and clinical outcomes of catheter ablation in patients with drug-refractory ventricular tachycardia who are ineligible for surgical intervention or implantable cardioverter defibrillators.

September 2, 1994European Heart Journal

Catheter Ablation of Ventricular Tachycardia

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Why the study?

Does catheter ablation prevent recurrence of ventricular tachycardia in patients with drug-refractory VT who are not candidates for surgery or ICD?

Population

80 patients with drug-refractory ventricular tachycardia who were not candidates for antitachycardic surgery…

Design

Case_series

Follow-up

Mean 12 months for CHD patients without recurrence, mean…

Authors

MBMartin BorggrefeElectrophysiology WHWilhelm HaverkampElectrophysiology GHG HindricksElectrophysiology

Discussion

Member takes

Implication

May support ablation for VT control in drug-refractory cases ineligible for ICD; leaves open randomized confirmation of benefit.

Key Points

To evaluate the efficacy and clinical outcomes of catheter ablation in patients with drug-refractory ventricular tachycardia who are ineligible for surgical intervention or implantable cardioverter defibrillators.
Treated 80 patients with drug-refractory ventricular tachycardia following endocardial catheter mapping with pacing interventions.
Applied direct-current energy (n = 61), radiofrequency energy (n = 13), or both (n = 6) to the site of origin or zone of slow conduction.
In 51 patients with coronary heart disease, 32 remained free of arrhythmia during a mean follow-up of 12 months, while 8 had recurrences, 2 suffered sudden death, and 3 died perioperatively.
In 29 patients without coronary artery disease, 21 had no recurrences during a mean follow-up of 17 months, whereas 8 experienced recurrence.

Structured PICO

Does catheter ablation prevent recurrence of ventricular tachycardia in patients with drug-refractory VT who are not candidates for surgery or ICD?

Population

80 patients with drug-refractory ventricular tachycardia who were not candidates for antitachycardic surgery or implantation of an automatic cardioverter defibrillator (51 with coronary heart disease, 29 without).

Intervention

Catheter ablation using direct-current (DC) (n=61), radiofrequency (RF) (n=13), or both (n=6) applied to the site of origin or zone of slow conduction after endocardial catheter mapping.

Outcome

Recurrence of ventricular tachycardia and mortalityhard clinical

Catheter ablation using DC or RF energy can prevent ventricular tachycardia recurrence in a substantial proportion of patients with drug-refractory VT who are not candidates for surgery or ICD.

Cite This Study

Borggrefe et al. (1994) studied this question.

synapsesocial.com/papers/6a778cd1249abce98a1e717f https://doi.org/10.1093/eurheartj/15.suppl_3.243

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Catheter Ablation of Ventricular Tachycardia

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Catheter Ablation of Ventricular Tachycardia

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider