Key result
The traditional sequential approach to HFrEF pharmacological therapy remains the standard of care, as non-traditional rapid sequencing lacks randomized clinical trial evidence.
The authors argue for maintaining the traditional sequential approach to HFrEF pharmacological therapy over rapid simultaneous initiation, citing the lack of RCT evidence for the latter.
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Neto et al. (2022) conducted an editorial in Heart failure with reduced ejection fraction (HFrEF). Traditional pharmacological treatment sequencing vs. Non-traditional rapid sequencing was evaluated. The traditional sequential approach to HFrEF pharmacological therapy remains the standard of care, as non-traditional rapid sequencing lacks randomized clinical trial evidence.
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