Initiating the four foundational pillars of HFrEF therapy within 4-6 weeks using a clinical profile-based sequencing approach may improve patient tolerance and therapeutic success compared to rigid historical sequencing.
May support profile-based HFrEF sequencing for faster foundational therapy; leaves open prospective validation before practice change.
A Brief History of Heart Failure (HF) Treatment Until 1987, HF treatment consisted in: None of these recommendations was based on clinical or epidemiological evidence, instead relying on the pathophysiological knowledge of the disease at the time, the pharmacological effect of medications, and good sense. […]
No takes yet. Share an insight, caveat, or question.
Luís Beck da Silva Neto (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:
More on HFrEF treatmentMore from ABC Heart Failure & Cardiomyopathy