Key result
Atrial fibrillation significantly raises the risk of Alzheimer's disease 1.5- to 2.5-fold, though vascular neuropathology rather than direct AD pathology may mediate this link.
Population
Patients with atrial fibrillation
Design
Review
Authors
Loading...
AF associated with higher AD risk; leaves open whether AF treatment modifies dementia incidence in observational data.
Effect estimate: 1.5- to 2.5-fold increased risk
This review highlights a potential mechanistic and epidemiological link between atrial fibrillation and Alzheimer's disease, suggesting that AF management strategies like ablation or anticoagulation may impact cognitive outcomes.
Ihara et al. (2018) conducted a review in Atrial fibrillation and Alzheimer's disease. Atrial fibrillation was evaluated on Alzheimer's disease (1.5- to 2.5-fold increased risk). Atrial fibrillation significantly raises the risk of Alzheimer's disease 1.5- to 2.5-fold, though vascular neuropathology rather than direct AD pathology may mediate this link.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: