Key result
Essential hypertension is associated with significant structural and hemodynamic changes in the abdominal aorta, including increased luminal diameter, elevated resistive index, and reduced end-diastolic velocity compared to normotensive controls.
Why the study?
The effects of essential hypertension on the luminal diameter and Doppler velocimetric indices of the abdominal aorta in adult patients required investigation.
Does essential hypertension alter the luminal diameter and Doppler velocimetric indices of the abdominal aorta in adults compared to normotensive controls?
Observational (n=254)
No
Does essential hypertension alter the luminal diameter and Doppler velocimetric indices of the abdominal aorta in adults compared to normotensive controls?
Answers are grounded in this paper and cite their sources.
Essential hypertension is associated with detectable structural and hemodynamic changes in the abdominal aorta, including increased resistive index and altered luminal diameter.
Objective: To investigate the effects of essential hypertension on the luminal diameter (caliber) and Doppler velocimetric indices of the abdominal aorta (AA) in adult patients with systemic hypertension. Materials and Methods: This was a prospective descriptive comparative study of 254 participants (127 with essential hypertension and 127 age/sex-matched controls). Their anthropometric parameters, fasting blood pressure, lipid profile, fasting blood sugar, and triplex sonography of the suprarenal and infrarenal abdominal aorta (Peak systolic velocity, PSV; End-diastolic velocity, EDV; Resistive Index, RI; and luminal diameter) were evaluated. The age group 60 - 69 years had the highest number of subjects and controls. The mean duration of hypertension in the subjects was 12.5 ± 5.2 years. The suprarenal and infrarenal abdominal aortic diameters (AAD) were higher in males than age-matched female counterparts. AAD increased with age mostly in hypertensive male subjects. PSV (in males) and RI (in both sexes) were elevated in hypertensive subjects compared to controls, while EDV (in both sexes) was significantly lower in subjects than controls. Multivariate linear regression showed that age and diastolic blood pressure were significant independent predictors for both suprarenal and infrarenal AADs. Conclusion: Systemic hypertension causes structural and hemodynamic changes in the abdominal aorta which are detectable on triplex sonography.
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Adetokunbo et al. (2022) conducted an observational in Essential hypertension (n=254). Essential hypertension vs. Normotensive controls was evaluated on Resistive Index (RI) of the suprarenal abdominal aorta (p=<0.0001). Essential hypertension is associated with significant structural and hemodynamic changes in the abdominal aorta, including increased luminal diameter, elevated resistive index, and reduced end-diastolic velocity compared to normotensive controls.
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