Key result
Enteric adenovirus 40/41 was detected by PCR in 5.3% of children with diarrhea compared to 1.7% of asymptomatic controls, and genetic analysis identified a novel AdV-41 strain with a 15-amino-acid deletion in the fiber gene.
Population
2,358 children from Kolkata, India, including 1,053 symptomatic children with diarrhea and 1,305…
Design
Cross-sectional
Authors
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Enteric AdV-40/41 was associated with pediatric diarrhea; leaves open the novel strain's role in virulence or transmission.
Cross-Sectional (n=2,358)
Yes
Absolute Event Rate: 5.3% vs 1.7%
A novel strain of enteric adenovirus 41 with a 15-amino-acid deletion in the fiber gene is circulating among children under 5 years of age in Kolkata, India.
Sharma et al. (2010) conducted a cross-sectional in Acute gastroenteritis (n=2,358). Enteric adenovirus 40/41 vs. Asymptomatic children was evaluated on Prevalence of enteric adenovirus 40/41 by PCR. Enteric adenovirus 40/41 was detected by PCR in 5.3% of children with diarrhea compared to 1.7% of asymptomatic controls, and genetic analysis identified a novel AdV-41 strain with a 15-amino-acid deletion in the fiber gene.
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