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July 1, 1970HeartOpen Access

Acute massive pulmonary embolism: Clinical and haemodynamic findings in 23 patients studied by cardiac catheterization and pulmonary arteriography

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Why the study?

What are the clinical and haemodynamic findings in patients with acute massive pulmonary embolism?

Population

23 patients with acute massive pulmonary embolism confirmed by pulmonary arteriography, with a history of…

Design

Case_series

Authors

GMGraham MillerAnalog Devices (United States)GSGeorge C. SuttonImperial College London

Discussion

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Implication

Alerts clinicians to expected haemodynamics in acute massive PE; single case report leaves broader applicability open.

Structured PICO

What are the clinical and haemodynamic findings in patients with acute massive pulmonary embolism?

P
Population
23 patients with acute massive pulmonary embolism confirmed by pulmonary arteriography, with a history of less than 48 hours' duration; only two had previous cardiorespiratory disease.
I
Intervention
Cardiac catheterization and pulmonary arteriography (diagnostic evaluation)
O
Outcome
Haemodynamic abnormalities including pulmonary artery systolic pressure, right ventricular end-diastolic pressure, arterial oxygen desaturation, arteriovenous oxygen difference, and cardiac outputsurrogate

Acute massive pulmonary embolism in patients without significant prior cardiorespiratory disease presents with moderate pulmonary hypertension, right ventricular failure, arterial oxygen desaturation, and low cardiac output.

Cite This Study

Miller et al. (1970) studied this question.

synapsesocial.com/papers/6a779b6a33def31403ae19b2https://doi.org/10.1136/hrt.32.4.518

Topics

Pulmonary embolism
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pulmonary embolism shock. Physiologic basis of a bedside screening test1966 · 36 citations
  2. 2Massive Pulmonary Thromboembolism1965 · 31 citations
  3. 3Streptokinase Therapy in Acute Major Pulmonary Embolism: Effectiveness and Problems1968 · 100 citations
  4. 4A Reappraisal of the Application of the Trendelenburg Operation to Massive Fatal Embolism1963 · 176 citations