Key result
Short-inversion time LGE CMR imaging detected more papillary muscle infarctions than standard LGE imaging (35.2% vs 27.8%) and improved contrast-to-noise ratio between PMI and blood (P=0.0157).
Why the study?
Does short-TI LGE CMR imaging improve the detection of papillary muscle infarction compared to standard LGE imaging in patients with myocardial infarction?
Observational (n=56)
Does short-TI LGE CMR imaging improve the detection of papillary muscle infarction compared to standard LGE imaging in patients with myocardial infarction?
Absolute Event Rate: 35.2% vs 27.8%
Short-inversion time LGE CMR imaging improves the sensitivity and contrast-to-noise ratio for detecting papillary muscle infarction compared to standard LGE imaging.
Short-TI LGE CMR may enhance PMI detection; leaves open whether improved visualization alters post-MI management or outcomes.
AIMS: Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging can detect myocardial scar in patients with myocardial infarction. The detection of papillary muscle infarction (PMI) may be difficult due to the bright blood signal. The aim of our study was to evaluate the incremental value of LGE CMR imaging using an inversion recovery (IR)-GRE with a short-inversion time (TI) over standard LGE imaging in identifying PMI. METHODS AND RESULTS: Fifty-six patients with myocardial infarction were studied using a standard IR-GRE LGE sequence with an adjusted TI to null the signal intensity of normal myocardium and with a 3D IR-GRE with a short TI (<180 ms). Signal-to-noise and contrast-to-noise ratios (CNR) and the frequency of PMI were determined. Image quality and infarction sharpness were evaluated. The short-TI LGE sequence detected a higher number of PMI compared with standard LGE sequence (19/54 vs. 15/54) with an increased sharpness of PMI (84.2 vs. 53.3%). The CNR was higher between infarcted myocardium and blood (77.9 ± 60 vs. 19.3 ± 16, P < 0.001) and between PMI and blood (69.4 ± 51 vs. 39.4 ± 26, respectively, P = 0.0157). CONCLUSIONS: Our data indicate that in patients with myocardial infarction, LGE CMR imaging using a short TI may be more sensitive than standard LGE imaging for the detection of PMI.
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Aldrovandi et al. (2012) conducted an observational in myocardial infarction (n=56). Short-inversion time (TI) LGE CMR imaging vs. Standard LGE imaging was evaluated on Frequency of papillary muscle infarction (PMI) detection. Short-inversion time LGE CMR imaging detected more papillary muscle infarctions than standard LGE imaging (35.2% vs 27.8%) and improved contrast-to-noise ratio between PMI and blood (P=0.0157).
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