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March 6, 2004European Journal of Cardio-Thoracic Surgery

Reoperations and late adverse outcome in Marfan patients following cardiovascular surgery☆

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Population

71 Marfan patients receiving first surgical treatment, including 22 patients presenting with acute aortic…

Design

Cohort

Follow-up

mean 5.2+/-1.8 years

Authors

TCThierry CarrelInterventional / Structural CardiologyLBLukas BeyelerETH ZurichASAurelia SchnyderUniversity of St.Gallen

Discussion

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Implication

Supports lifelong surveillance after root replacement in Marfan syndrome; extends observational data but remains hypothesis-generating for optimal protocols.

Structured PICO

P
Population
71 Marfan patients (mean age 29+/-17 years, range 8-65 years) receiving first surgical treatment, including 22 patients (31%) presenting with acute aortic dissection.
I
Intervention
Initial cardiovascular surgery, primarily aortic root repair or replacement (composite graft replacement in 85%, aortic valve sparing root repair in 7 patients).
O
Outcome
Incidence of cardiovascular lesions, reoperations, and clinical follow-up outcomes (mortality and morbidity) after initial surgery.hard clinical

Marfan patients require close lifelong clinical and imaging follow-up after initial aortic root surgery due to a high risk of reoperations, particularly in those presenting with acute dissection, and the risk of fatal rupture even in normal-sized aortic segments.

Cite This Study

Carrel et al. (2004) studied this question.

synapsesocial.com/papers/6a77a2d87ecc675f86ae8a0ahttps://doi.org/10.1016/j.ejcts.2004.01.034
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Surgical treatment of cardiovascular complications in Marfan syndrome: a 27-year experience1992 · 14 citations
  2. 2Reoperation after Type A Dissection Repair2008 · 4 citations
  3. 3Repeated surgery for recurrent dissection of the aorta1990 · 21 citations
  4. 4Early and Long-Term Results of a Valve-Sparing Operation for Marfan Syndrome1999 · 62 citations