Key result
Ginseng gut microbiome metabolites demonstrated significant anti-angiogenic effects on pulmonary, gastric, and ovarian cancers, suggesting potential utility in cancer chemoprevention.
Population
Cancer models (pulmonary, gastric, and ovarian cancers)
Design
Review
Authors
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No immediate clinical adoption for chemoprevention; leaves open need for prospective human trials.
Ginseng metabolites, particularly ginsenoside Rg3 and compound K, demonstrate anti-angiogenic properties that may be useful in combination with standard chemotherapeutic agents for cancer management.
Wang et al. (2015) conducted a review in Cancer. Ginseng metabolites (ginsenoside Rg3 and compound K) was evaluated on Cancer chemoprevention, apoptosis, and angiogenic inhibition. Ginseng gut microbiome metabolites demonstrated significant anti-angiogenic effects on pulmonary, gastric, and ovarian cancers, suggesting potential utility in cancer chemoprevention.
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