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October 19, 1957JAMA

Open Heart Surgery

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Why the study?

Does open heart surgery using extracorporeal circulation result in acceptable survival rates in patients requiring cardiac correction?

Population

53 patients undergoing open heart surgery, including 30 for the correction of aortic stenosis and 4 for…

Design

Case_series

Authors

KKKenneth K. Keown

Discussion

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Overview

High mortality from ventricular fibrillation warrants caution with extracorporeal circulation; leaves open optimization for tetralogy of Fallot and similar defects.

Structured PICO

Does open heart surgery using extracorporeal circulation result in acceptable survival rates in patients requiring cardiac correction?

P
Population
53 patients undergoing open heart surgery, including 30 for the correction of aortic stenosis and 4 for tetralogy of Fallot.
I
Intervention
Open heart surgery using extracorporeal circulation (pump-oxygenator).
O
Outcome
Survival/mortalityhard clinical

Early experience with open heart surgery using extracorporeal circulation demonstrated its feasibility for correcting defects like aortic stenosis and tetralogy of Fallot, though with notable mortality risks primarily from ventricular fibrillation.

Cite This Study

Kenneth K. Keown (1957) studied this question.

synapsesocial.com/papers/6a77c7eaa7498e5110aedbf5https://doi.org/10.1001/jama.1957.02980250015004
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1COMPLETE CORRECTION OF THE TETRALOGY OF FALLOT BY OPEN-HEART SURGERY1959 · 13 citations
  2. 2The Birth of Open-Heart Surgery: Then the Golden Years1994 · 14 citations
  3. 3Milestones in Surgery: 60 Years of Open Heart Surgery2014 · 11 citations
  4. 4Medical Aspects of Open-Heart Surgery1966 · 23 citations
  5. 5Redo Resection of Residual Right Ventricular Outflow Tract Obstruction in a Postoperative Case of Tetralogy of Fallot under Moderately Hypothermic Extracorporeal Circulation and Cardioplegic Arrest: A2020