Prolonged Postoperative Disorientation After Methylene Blue Infusion During Parathyroidectomy

In Brief Methylene blue 7.5 mg/kg is frequently given at our institution during parathyroidectomy. The dye preferentially stains the parathyroids so as to provide better surgical visualization. Other than causing a pseudocyanosis, the technique is generally considered to be rather innocuous. We report a case of a patient who, after this procedure, had a postoperative course that was unusual because of slowly resolving altered mental status. IMPLICATIONS: We report the case of a patient who, after a large dose of methylene blue, had a postoperative course that was unusual because of slowly resolving altered mental status.