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June 2, 2021Open Access

At 12 postoperative months, the union rate was 80.76% in the open reduction group and 82.35% in the closed reduction group (p=0.787), but the required time to union was significantly shorter in the open reduction group (7.39 vs. 9.18 months, p=0.025).

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Why the study?

This study aimed to determine whether outcomes of femoral diaphyseal fractures (AO/OTA/32-C) depended on the treatment technique of closed versus open reduction and internal fixation with an interlocking nail.

Does open reduction compared to closed reduction improve radiographic outcomes and union time in patients with complex femoral shaft fractures?

Population

47 consecutive patients with femoral diaphyseal fractures (AO/OTA/32-C) at a level III trauma center

Comparison

Closed reduction vs open reduction and internal fixation with an interlocking nail

Design

Retrospective study

Follow-up

12 postoperative months

Authors

YCYu‐Hung ChenSLShang‐Ming LinCCChih-Hung Chang

Discussion

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Member takes

Overview

Closed reduction was associated with better outcomes in complex femoral fractures; leaves open optimal technique pending randomized confirmation.

Structured PICO

Does open reduction compared to closed reduction improve radiographic outcomes and union time in patients with complex femoral shaft fractures?

P
Population
47 consecutive patients with femoral diaphyseal fractures (AO/OTA/32-C) treated at a level III trauma center
I
Intervention
Open reduction and internal fixation with an interlocking nail
C
Comparator
Closed reduction and internal fixation with an interlocking nail
O
Outcome
Radiographic union score of the femur, mean union time, re-operation rate, and complication ratesurrogate

Open reduction for complex femoral shaft fractures yields similar union rates to closed reduction but significantly shortens the time to union without increasing complications.

Cite This Study

Chen et al. (2021) studied this question.

synapsesocial.com/papers/6a77d1cbc5ab23c76cecef13https://doi.org/10.21203/rs.3.rs-539520/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Comparison of Complications and Union Rates in Intramedullary Nailing of Femoral Shaft Fractures Treated With Open Versus Closed Reduction2019 · 14 citations
  2. 2Comparison of Open and Closed Nailing for Femoral Shaft Fractures: A Retrospective Analysis2021 · 13 citations
  3. 3Comparative study on femoral shaft fracture treated by plate and screws versus intramedullary interlocking nails. A clinical study2025
  4. 4Open versus Closed Intramedullary Nailing of Femoral Shaft Fractures1986 · 32 citations
  5. 5Outcome of femoral shaft closed fracture treated by interlocking nail in patients presenting to a tertiary care hospital.2025